Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Moderately Good
Based on 70 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Ubiquinol (Kaneka Ubiquinol™) (Reduced Form CoQ10)
100 mg
**
Top Medical Research Studies
9
Mitochondrial cocktail enhances heart protection
We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
Read More
9
Combination therapy improves heart health
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
Read More
Most Useful Reviews
9
Indispensable assistant
216 people found this helpful
I regularly take ubiquinol every morning after a heart attack. It's proven effective for my heart defect and improves my energy levels and memory significantly. I no longer require other medications as this helps normalise my blood pressure. Although pricier, its benefits make it worthwhile.
Read More
9
Notable improvements
10 people found this helpful
After worsening heart problems and little success with prescribed treatments, I tried ubiquinol. Within three days of use after my heart attack, I felt significant improvement, including better sleep and energy levels.
Read More
9
Increased energy
8 people found this helpful
I took a jar for myself, my mother, and my aunt. We are all delighted, feeling a clear boost in energy. After long days, there's lightness in my body, fewer painful periods, fewer heart interruptions, and I can breathe deeply. I will order more to see the effects of prolonged use.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
- All Researches
9
Combination therapy improves heart health
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
Read More
9
Mitochondrial cocktail enhances heart protection
We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 70 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Indispensable assistant
216 people found this helpful
I regularly take ubiquinol every morning after a heart attack. It's proven effective for my heart defect and improves my energy levels and memory significantly. I no longer require other medications as this helps normalise my blood pressure. Although pricier, its benefits make it worthwhile.
Read More
9
Notable improvements
10 people found this helpful
After worsening heart problems and little success with prescribed treatments, I tried ubiquinol. Within three days of use after my heart attack, I felt significant improvement, including better sleep and energy levels.
Read More
9
Increased energy
8 people found this helpful
I took a jar for myself, my mother, and my aunt. We are all delighted, feeling a clear boost in energy. After long days, there's lightness in my body, fewer painful periods, fewer heart interruptions, and I can breathe deeply. I will order more to see the effects of prolonged use.
Read More
9
Increased vigour
8 people found this helpful
It's critically important for mitochondria. My energy has increased dramatically! I no longer feel sleepy after lunch, and I'm more focused under work stress. It’s essential for heart patients and diabetics. I will order more despite the high price.
Read More
9
Post-heart attack recovery
5 people found this helpful
Excellent! My mother, aged 70, suffered a heart attack and has had arrhythmia attacks. She feels fine now after taking this supplement alongside omega 3.
Read More
Frequently Asked Questions
9
Notable improvements
10 people found this helpful
After worsening heart problems and little success with prescribed treatments, I tried ubiquinol. Within three days of use after my heart attack, I felt significant improvement, including better sleep and energy levels.
9
Increased strength
2 people found this helpful
The effects of Ubiquinol are noticeable within days. My strength improved, and my heart no longer flutters during physical activity. It enhances my quality of life significantly by assisting in ATP production, essential for our body’s energy.
9
Less fatigue outdoors
1 people found this helpful
My energy levels improved significantly after a week of taking it. Previously, I would tire easily due to diminished heart function, but now I feel invigorated when going out. Those with mitochondria damage should consider this product.
7.5
Hypertension improvement
2 people found this helpful
My husband and I have been taking Ubiquinol for two months. It has greatly improved his heart condition, allowing him to stop hypertension medication.
7.5
Supports heart health
1 people found this helpful
Excellent! In December, I began improving my immunity with a nutritionist. Ubiquinol was one of the supplements prescribed. Coenzyme Q10 maintains women's health by supporting reproductive function, stabilising hormonal balance, and reducing the risk of heart attack. After six months, I've certainly noticed positive results.
9
Indispensable assistant
216 people found this helpful
I regularly take ubiquinol every morning after a heart attack. It's proven effective for my heart defect and improves my energy levels and memory significantly. I no longer require other medications as this helps normalise my blood pressure. Although pricier, its benefits make it worthwhile.
9
Increased vigour
8 people found this helpful
It's critically important for mitochondria. My energy has increased dramatically! I no longer feel sleepy after lunch, and I'm more focused under work stress. It’s essential for heart patients and diabetics. I will order more despite the high price.
9
Stronger heart
3 people found this helpful
I feel my heart is stronger after six months of taking it.
9
Post-heart attack recovery
5 people found this helpful
Excellent! My mother, aged 70, suffered a heart attack and has had arrhythmia attacks. She feels fine now after taking this supplement alongside omega 3.
9
Arrhythmia relief
5 people found this helpful
I bought it for my wife, who had an operation for tachycardia and arrhythmia. After starting CoQ10 and ubiquinol, her heart pain ceased and she even enjoyed wine on New Year's Eve. There are no side effects.
6
Cardiovascular maintenance
232 people found this helpful
I take this food supplement following a heart attack to support the normal functioning of my cardiovascular system.
9
Heart protection
4 people found this helpful
I take Coenzyme Q10 to protect my heart and support energy production while combating free radicals. It’s essential for heart health; I take 200mg daily.
9
Increased energy
2 people found this helpful
I ordered this for my 66-year-old mother. She finds it more effective than CoQ10. It has vastly improved her energy, making mornings easier and reducing heart discomfort. For optimal absorption, it’s best taken with fatty foods.
9
Combination therapy improves heart health
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
9
Mitochondrial cocktail enhances heart protection
We designed a study with male Wistar rats, aged 22-24 months and induced with type-2 diabetes, to investigate how a combination of three mitochondrial agents—melatonin, nicotinamide mononucleotide (NMN), and ubiquinol—could provide protection against myocardial ischemia/reperfusion (I/R) injury, especially in the context of aging and diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
The rats were split into groups receiving different treatments, including some that received the cocktail of supplements just during the reperfusion phase after inducing I/R injury. Over 28 days leading up to the tests, rats received NMN, while melatonin and ubiquinol were administered as the heart was being revived after ischemia.
The results indicated that the combination therapy notably enhanced heart protection and improved mitochondrial function and biogenesis in these aged diabetic rats. While ubiquinol was an important part of this cocktail, it is essential to view its role as one among several synergistic agents. This points to exciting possibilities for improved heart health strategies, particularly for older individuals with diabetes.
References
- Mokhtari B, Jessri A, Ghaffari S, Badalzadeh R. Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats. Adv Pharm Bull. 2024;14:686. doi:10.34172/apb.2024.044
- Mokhtari B, Høilund-Carlsen PF, Chodari L, Yasami M, Badalzadeh R, et al. Melatonin/nicotinamide mononucleotide/ubiquinol: a cocktail providing superior cardioprotection against ischemia/reperfusion injury in a common co-morbidities modelled rat. Mol Biol Rep. 2023;50:3525. doi:10.1007/s11033-022-08189-0
